Resumo

MARQUES, Tárcia Virgínia Falcão; GONCALVES, Lucio  e  MARQUES, Fábio Vidal. Influence of apical periodontitis on serum levels of C-reactive protein: literature reviewd. Rev. Bras. Odontol. [online]. 2015, vol.72, n.1-2, pp. 16-19. ISSN 1984-3747.

Apical periodontitis is a bacteria-induced disease that activates the localized release of pro-inflammatory mediators capable of inducing the production of acute-phase proteins (like C-reactive protein) by the liver. Even mild elevations of serum levels of CRP are associated with higher cardiovascular risk. Literature shows many studies that evaluates the correlation between periodontal disease, inflammatory markers (like CRP and IL6) and cardiovascular diseases. However, few studies have assessed the possible association between chronic apical periodontitis or history of endodontic treatment and cardiovascular diseases. The aim of the present review was to assess the current evidence regarding the possible association between chronic apical periodontitis and elevation of serum CRP.

Palavras-chave : C-reactive protein; periapical periodontitis; inflamation; cardiovascular diseases..