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Revista da Associacao Paulista de Cirurgioes Dentistas

  ISSN 0004-5276

CRISTHIANE OLIVIA FERREIRA DO, Amaral et al. Physical and oral characteristics in patients with fragile X syndrome. Rev. Assoc. Paul. Cir. Dent. []. 2012, 66, 2, pp. 128-135. ISSN 0004-5276.

The fragile X syndrome is a genetic disorder, identified microscopically by a constriction called fragile site on the long arm of chromosome X, considered the main inherited cause of mental disability associated with several neurological disorders. The aim of this study were analyzed physical and oral characteristics, medical problems and behavioral characteristics in patients with fragile X syndrome, and diffuse this syndrome among dentists. Volunteers (n=31) with fragile X syndrome were submitted a structured form, physical and oral exam and the multidisciplinary form was analyzed. The data were submitted to statistical analyses (Chi-square; P<.05). Regular use of medicine was reported by 68% (P<.05), the most commonly used was the anticonvulsants (61%). The presence of biofilm (93%) and gingivitis (81%) was statistically significant when the amount of positive and negative cases were compared. Malocclusion and atresic palate were present in 93% of the volunteers (P<.05). All subjects reported the presence of family history of mental retardation. Among the facial features elongated face, ears and forehead prominent and behavioral aspects of hyperactivity and anxiety were statically significant differences. Thus, we conclude that there are large variability among the characteristics expressed by individuals with the Fragile X syndrome, frequently these individuals have elongated face, prominent ears and mental retardation associated with oral problems such as malocclusion, atresic palate and enamel hypoplasia. In addition poor oral hygiene and regular medicine is common in this patients.

: fragile X syndrome; oral health; face; behavior; human characteristics.

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