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Objective: The aim of this study was to review the previous publications of the EndoSequence BC Sealer in order to evaluate the results obtained using this sealer with regards to its biological and physicochemical properties; therefore, analyzing several areas of its performance and possible outcomes of its clinical use in a more reliable way. Material and Methods: A search of the literature was performed for the identification of all published articles using the EndoSequence BC Sealer, considering studies that evaluated its biological and physicochemical properties. The strategy of the search was based on access to the PubMed and Bireme databases. Results: Thirty-two manuscripts met the inclusion criteria and were used in this review. These manuscripts demonstrated that the sealer has adequate radiopacity, flow, solubility, and dimensional changes. Furthermore, the sealer has antimicrobial activity and is biocompatible. Conclusion: A review of the relevant literature suggests that the EndoSequence BC Sealer has demonstrated satisfactory performance in some important properties for a root canal sealer

: Endodontics; Silicate cement; Root canal obturation.