SANTOS, Poliana Ramos Braga et al. Prevalence of orofacial alterations in sickle cell disease: a review of literature. Braz. J. Oral Sci. []. 2013, 12, 3, pp. 153-157. ISSN 1677-3225.

AIM: To evaluate the manifestations of sickle cell disease on the orofacial complex through a review of current literature concerning prevalence of dental caries, periodontal disease, temporomandibular joint disorders and radiographic alterations of maxillofacial bones. METHODS: Full-text papers retrieved from MEDLINE and LILACS electronic databases were critically reviewed. RESULTS: Alterations of maxillofacial bones are well documented in the literature, but studies reporting caries, periodontal condition and temporomandibular joint alterations in are scarce and inconclusive. CONCLUSION: Further well-designed epidemiological studies are needed to indicate the real impact of this disease on the stomatognathic health, collaborating to improve public health policies.

: sickle cell anemia; hemoglobin C disease; dental caries; periodontal diseases; temporomandibular joint; diagnostic X-ray..