ALMEIDA, Ulysses de et al. Biomaterial's analysis and use, made of crassostrea gigas shells in rats' periondontal defects. Odontol. Clín.-Cient. (Online) []. 2011, 10, 3, pp. 259-263. ISSN 1677-3888.

Oyster shells may be presented as a potential source for the production of a bone graft biomaterial, once they are mainly constituted by calcium. The aim of this study was to evaluate the effects of a biomaterial based on Crassostrea gigas shell in the application of periodontal defects in rats.MEV analysis of the particles showed a variety of sizes and microporous surface, while EDXRF analysis demonstrated calcium oxide as the main component. Two groups of 20 WISTAR rats received periodontal defects filled with either blood clot or the test biomaterial. Monitoring periods were 1, 3, 6 and 8 weeks. Histological analysis revealed a chronic granulomatous process; more edema than control; an initial fibrous osteoid tissue; a thin layered bone repair; a fibroplasic aspect of the periodontal ligament; and in an advanced stage, ankylosis. It can be concluded that the application of the biomaterial in the periodontal defect of this study was unfavorable.

: Crassostrea; Periodontal defect; Bone substitute; Periodontal Dislases; Bone Transplantation; Biocomplative Materials..