ORZECHOWSKI, Paulo Roberto et al. Central giant cell granuloma: a case report. Rev. cir. traumatol. buco-maxilo-fac. []. 2012, 12, 4, pp. 61-68. ISSN 1808-5210.

This study reports a case of central giant cell granuloma and also presents a review of the literature, focusing on the diagnosis and management of this lesion. A 25-year-old caucasian male, came to the Maxillofacial Surgery Outpatient Clinic of the University of Taubaté presenting a large lesion in the left mandibular body. Radiographic and computed tomography (CT) examinations revealed a unilocular radiolucent area suggesting the diagnoses of ameloblastoma, central giant cell granuloma and aneurysmal bone cyst. We performed an incisional biopsy, which revealed the presence of multinucleated giant cells embedded in a collagenous stroma with areas of extravasation of erythrocytes and hemosiderin deposits. Complementary biochemical examinations of the serum, demonstrated normal levels of alkaline phosphatase, calcium, phosphorus and parathyroid hormone. The treatment was surgical curettage of the lesion with preservation of the teeth involved. After twenty-four months of follow-up the patient shows a full recovery with no signs of recurrence and clear new bone formation, as evidenced by clinical and radiographic analyses

: Granuloma; Giant Cell; Mandible; Surgery; Diagnosis; Treatment.