Abstract

LUKSCHAL, Luis Felipe  and  LEAL, Rosana Maria. Apoptotic index in periapical cysts with atrophic and hyperplastic epithelium. Rev. cir. traumatol. buco-maxilo-fac. [online]. 2012, vol.12, n.4, pp. 91-98. ISSN 1808-5210.

Objectives: This study describes the occurrence of apoptosis in periapical cysts with atrophic and hyperplastic epithelium, making a morphologic study quantifying the apoptotic indices and verifying the quantitative differences between them. Methodology: 15 samples of periapical cyst with most of the epithelial lining represented by the atrophic type and 15 samples with most of the epithelium lining represented by the hyperplastic type were selected, all originating in the Anatomical Pathology Laboratory of the Dental School, Pontificia Universidade Católica of Minas Gerais. The blocks were cut into 4µm-thick sections and stained with hematoxilina and eosine (HE) for performing the histopathologic diagnosis and with methyl (MGP) for evaluation of the occurrence of apoptotic cells. For the confirmation of apoptosis the tunnel method was used. Results: The statistical analysis comparing the atrophic and hyperplastic epithelium of the periapical cysts showed that there were no statistically significant differences between these two types of epthelium (p>0.05).

Keywords : Cell physiology; Cell death; Apoptosis; Stomatognathic diseases; Jaw diseases; Jaw cysts; Odontogenic cysts; radicular cyst..