Resumo

VIEIRA, Hugo Geraldo Perdigão e et al. Biochemical mechanism involved in root resorption caused by treatment orthodontic. RGO, Rev. gaúch. odontol. (Online) [online]. 2011, vol.59, suppl.1, pp. 103-111. ISSN 1981-8637.

Considered, by many authors, as one of the most usual sequelae of orthodontic treatment, root resorption was the focus of this review of literature, which aimed to reexamine and clarify the biochemical mechanisms of resorption, as well as influent factors, either individual or regarding the very orthodontic treatment. Literature showed that the process of root resorption is connected to hyalinization of the periodontal ligament, and initiates concurrently with the removal of hyalinized tissue; also, it appears to be regulated by the same modulators, such as prostaglandins, interleukins and tumor necrosis factor-a, showing a close relationship to inflammation mechanisms. Root resorption could also be inhibited by calcium metabolism-associated substances that are related to one or more odontoclastic functions: thyroid hormone (T4), bisphosphonates, calcitonin, echistatin, and others. Prolonged resorption after orthodontic treatment could be related to other causes not specifically involved in the treatment.

Palavras-chave : Tooth movement.; Orthodontics.; Tooth resorption..