Resumo

STEFFENS, João Paulo; SANTOS, Fábio André  e  PILATTI, Gibson Luiz. COX-2 selective nonsteroidal anti-inflammatory drugs and pain control after periodontal surgeries: a pilot study. RGO, Rev. gaúch. odontol. (Online) [online]. 2012, vol.60, n.1, pp. 85-89. ISSN 1981-8637.

Objective The purpose of this pilot study was to evaluate the effectiveness of two COX-2 selective non-steroidal anti-inflammatory drugs on pain control after open flap debridement. Methods For this parallel, double-blind, placebo-controlled randomized clinical trial, 18 open flap debridement procedures were performed in patients from the Department of Periodontology of Universidade Estadual de Ponta Grossa with periodontal disease after nonsurgical treatment in at least one sextant. The patients were randomly allocated to one of the following groups and medicated one hour before surgery: G1- 200 mg celecoxib (n=6); G2- 90 mg etoricoxib (n=6); G3- placebo (n=6). Pain intensity was then assessed by the visual analogue scale and 101-point numerical rating scale within 8 hours of surgery. Results Pain intensity in G2 was significantly lower than in G3 1 and 3 hours after surgery. Conclusion The use of a preemptive single-dose of 90 mg etoricoxib proved to be effective for initial pain control after open flap debridement. NCT00970112.

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