Abstract

PAIVA, Monique Danyelle Emiliano Batista et al. Salivary flow and Epidermal Growth Factor (EGF) levelsin saliva of type 2 diabetic patients. Odontol. Clín.-Cient. (Online) [online]. 2010, vol.9, n.3, pp.235-237. ISSN 1677-3888.

The aim of this study was to evaluate the salivary flow and the concentration of EGF in saliva of diabetic patients not insulin-dependents compared with a non diabetic patients (control group). Stimulated saliva was collected in two groups of patients: G0 - control (n=9) and G1 - diabetics (n=6), using a hiperbolóide. Saliva was expelled in the first minute and it was despised. In the following five minutes it was collected with a funnel connected to a graduated tube. EGF concentration measurement was performed using a sandwich-type immunoassay, using an ELISA Kit (R&D Systems®) and a microplate reader. It was observed an average of salivary flow of 1.27ml/min. in G0 and 1.26ml/min. in G1 and it was not found significant differences between the two groups (p=0.972). It was also observed an average of 1624.08 pg/ml of EGF in the G0 and 2367.66 pg/ml in the G1 and as the salivary flow the difference was not statistically significant (p=0.559). The data present in this work demonstrate no differences between salivary flow and EGF concentration of diabetic patients as compared as non-diabetic patients.

Keywords : Saliva; Epidermal Growth Factor; Diabetes Mellitus.

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