Abstract

GIACOMO, Valéria Di; COMAR, Lívia Picchi; SALOMAO, Priscila Maria Aranda  and  MAGALHAES, Ana Carolina. The effect of paste containing hydroxyapatite nanoparticles and fluoride on dentin demineralization. Rev. Assoc. Paul. Cir. Dent. [online]. 2014, vol.68, n.2, pp. 112-116. ISSN 0004-5276.

This study evaluated the potential of an experimental formulation containing HAP and sodium fluoride to reduce bovine dentin demineralization in vitro. Eighty-four bovine roots dentin samples were divided into 7 groups of 12 samples and subjected to one of the following treatments: 1) Nanop plus paste (HAP 20% + 9000 ppm F, NaF); 2) Nanop paste (HAP 20%) 3) F paste (9000 ppm F, NaF); 4) placebo paste (without HAP and F); 5) MI paste (casein and calcium phosphate); 6) MI Paste plus (casein and calcium phosphate, 900 ppm F, NaF); 7) no treatment (control). The treatments were performed twice a day, interspersed by pH cycling (de-remineralization) for 7 days. Thereafter, the samples were analyzed using surface and cross-sectional microhardness (10-220 μm). The data was plotted and statistically analyzed (p<0.05). The treatments that produced a significant effect on the reduction of dentin demineralization were Nanop plus and F pastes only. Therefore, the data confirmed that fluoride is still the best chemical agent to control dental demineralization. The experimental paste containing HAP nanoparticles was ineffective in reducing dentin demineralization when using this experimental model.

Keywords : dentin; demineralization; fluoride.