Abstract

MEDEIROS, Luanna Abílio Diniz Melquiades de et al. Chitosan/D. ambrosioides (mastruz) spheres to be applied as a biomaterial. Rev. Bras. Odontol. [online]. 2016, vol.73, n.2, pp. 124-129. ISSN 1984-3747.

Objective: This worked aimed to develop chitosan/D. ambrosioides (mastruz) spheres to be applied as a biomaterial. Material and Methods: To obtain the chitosan spheres and the chitosan with crude ethanolic extract of mastruz (CEE) the Ionotropic gelation technique was used. Four groups were formed: QO- Chitosan; Q5; Q10 and Q20, Chitosan with 5%, 10% and 20% of CEE, respectively. Were characterized by Optic Microscopy (OM); Cytotoxicity and Biodegradation.Results: InOM, well delimited and darker spheres were observed, as the CEE percentage increased. All groups were noncytotoxic. In the presence of lysozyme, mass loss was observed, as for in solution Phosphate Buffered Saline (PBS) the mass gain was found. Conclusion: It can be concluded that the spheres presented potential for use as a biomaterial.

Keywords : chitosan; medicinal plants; bone regeneration..