Abstract

RUI, Graciele et al. Unusual case of erythema multiforme. RFO UPF [online]. 2016, vol.21, n.1, pp. 96-101. ISSN 1413-4012.

Introduction: Erythema multiforme (EM) is a disease that may affect skin and mucous membranes, and has major clinical importance because of the frequency and variety of entities that it may represent. It is difficult to diagnose, likely because of patient hypersensitivity. Objective: This study aims to report an unusual case of EM related to antidepressant use. Case report: Female patient, 38 years old, reporting the appearance of ulcers preceded by blisters in the oral cavity about a month after starting antidepressant treatment using bupropion hydrochloride. The history and clinical aspects of skin and oral lesions were assessed, as well as histopathological and immunofluorescence findings, thus excluding differential diagnoses and obtaining the diagnosis of EM. The patient was treated with topical and systemic oral corticosteroids, removing the antidepressant drug. Final considerations: Because this disease may affect the oral cavity, resulting in extensive ulcerative lesions that are very uncomfortable to the patient, the dentist should know its clinical, diagnosis, treatment, and prognosis aspects.

Keywords : Antidepressive agents.; Erythema multiforme.; Diagnosis.; Therapy..