Abstract

OLIVEIRA, Paula Prieto  and  NUNES, Fábio Daumas. Oral smooth muscle tumors: analysis of 49 cases and literature review . Odontol. Clín.-Cient. (Online) [online]. 2013, vol.12, n.1, pp. 53-57. ISSN 1677-3888.

The aim of this study is to analyse and compare the clinical features of leiomyoma and leiomyosarcoma, because they help in the differential diagnosis. Records from Oral Pathology Department of Dental School at University of São Paulo during the period 1962-2010 were analysed. There were 49 cases of smooth muscle tumors: 27 leiomyomas and 22 leiomyosarcomas. Cases of smooth muscle tumors of the oral cavity were also compiled from 1970 to 2010. These tumors represented 0,092% of all oral lesions, with similar distribution between genders. Leiomyoma was more frequent in the fifth decade of life. The lips and the tongue were the most common sites. The majority of cases were asymptomatic. The accomplished treatment was surgical excision, with excellent prognosis. Leiomyosarcoma was more frequent in patients up to 50 years and the jaws were the most affected sites. The majority of cases were symptomatic and the pain was the most present symptom. Complete surgical resection was the most appropriate treatment. The recurrence rate was 27%, with 24% of metastasis and 30% of mortality, demonstrating the bad prognosis of this lesion.

Keywords : Leiomyoma; eiomyosarcoma; epidemiology; mouth.