Abstract

AVELAR, Rafael Linard et al. Granular cell tumor of the tongue: a case report. Rev. cir. traumatol. buco-maxilo-fac. [online]. 2010, vol.10, n.1, pp. 39-42. ISSN 1808-5210.

The granular cell tumor is an uncommon benign tumor occurring in several parts of the body, being found normally in the maxilla, skin and gastrointestinal or respiratory tracts. The tongue and buccal mucosa are the most frequent intraoral sites. Its causation is only partially understood and it has been a source of controversy since it was first reported. Based on immunohistochemical and histopathological findings, different origins have been proposed, such as muscular, neural or connective tissue. A case of granular cell tumor on the tongue of a female patient is reported. On the basis of an excisional biopsy, the histopathological examination revealed eosinophilic granular cells labeled with the S-1000 protein, supporting the neural origin of the lesion and confirming the diagnosis of a granular cell tumor.

Keywords : Granular Cell Tumor; Schwann Cells; Tongue Neoplasms.