Abstract

HILGERT, Rafael; FONSECA, Luiz Afonso Morgenstern da; RIBEIRO, Felipe Friedrich  and  SOARES, Leonardo Yoshiura. Solitary plasmacytoma of the mandible: a case report. Rev. cir. traumatol. buco-maxilo-fac. [online]. 2012, vol.12, n.3, pp. 67-72. ISSN 1808-5210.

Plasma cells represent the final maturation stage of B lymphoid cells. They normally originate in the bone marrow and specialize in producing immunoglobulin. Plasmacytoma is characterized by a monoclonal neoplastic proliferation of plasma cells and the course of the disease may be confined to one medullary area of the bone - solitary osseous plasmacytoma (SOP), to one extramedullary area - extramedullary plasmacytoma (EMP), or may, in the case of multiple myeloma, involve many areas. This article describes a case of solitary osseous plasmacytoma of the jaw diagnosed at an early stage in a 63-year-old patient and treated with 25 sessions of radiotherapy totaling 45 Gy. As such a lesion represents an early stage of multiple myeloma, rather than a distinct clinical condition, and the diagnosis is rarely performed in the early stages of the disease, important issues relevant to early diagnosis and the long-term follow-up are addressed.

Keywords : Plasmacytoma; mandible; multiple myeloma..