Abstract

ARRUDA, José Alcides Almeida de  and  SAMPAIO, Gerhilde Callou. Stevens-Johnson syndrome associated with allopurinol and nimesulide: case report. Rev. cir. traumatol. buco-maxilo-fac. [online]. 2014, vol.14, n.3, pp. 59-64. ISSN 1808-5210.

The Stevens-Johnson syndrome (SJS) is a variant of erythema multiforme by the conformation and distribution of skin lesions and more severe mucosal involvement. It is characterized by the action of specific drugs for IgG or IgM antibodies. Plays an important role in dentistry since often the first manifestations of this disease occur in the oral mucosa. The objective of this paper is to present a report of a patient with SJS, male, 53 years, with an initial complaint of pain and burning mouth. On clinical examination there was injury and hemorrhagic crusts evident in the vermilion of the lips and buccal mucosa. Reported that previously serviced on an eye care center and diagnosed with conjunctivitis and was under use of the following medications: allopurinol,nimesulide, simvastatin, omeprazole and front. The patient's condition progressed rapidly to skin lesions and for this hospital and subjected to the burning of a private hospital sector protocol reason. Currently the patient has the following consequences: blindness of the left eye, nasal pterygium and symblepharon. Knowledge of this syndrome, the dentist is crucial, since the establishment of early diagnosis can minimize sequelae and even prevent extreme cases death. Finally, clarify and educate professionals about the indiscriminate use of medicines, now recognized to cause this syndrome.

Keywords : Erythema multifome major; Stevens-Johnson Syndrome; Vesicular bullous lesions..