Abstract

KAARTHIKEYAN, Gurumoorthy et al. Management of mucous membrane pemphigoid with dapsone plus weekly steroid injections in a young patient: a case report. Rev. odonto ciênc. (Online) [online]. 2010, vol.25, n.1, pp. 97-99. ISSN 1980-6523.

PURPOSE: Mucous Membrane Pemphigoid (MMP) is an autoimmune subepithelial blistering disorder usually affecting older individuals. This paper describes the pharmacological management of MMP in a young patient. CASE DESCRIPTION: A 23 year-old woman showed erythematous ulcerative gingiva in the maxillary palatal region and around the retromolar region. A perilesional excisional biopsy was done, and the histologic and immunohistochemical analysis confirmed the clinical diagnosis of MMP as the cause of desquamative gingivitis in this patient. The patient was treated with topical steroids plus daily Dapsone 100 mg and weekly steroid injections (40 mg). The lesions began to resolve after 12 weeks of therapy. CONCLUSION: This case of MMP in a young female patient was effectively managed with a combination therapy of topical steroids, Dapsone and steroid injections.

Keywords : Pemphigoid; topical steroids; dapsone; steroid injections; immunofluorescence.