Abstract

LISBOA, Alessandro Hyczy  and  PILATT, Gibson Luiz. Pain control with dexamethasone, etoricoxib or ibuprofen associated with arginine in impacted third molar surgery. RGO, Rev. gaúch. odontol. (Online) [online]. 2013, vol.61, n.3, pp. 335-340. ISSN 1981-8637.

Objective The aim of this study was to perform a comparative evaluation of postoperative analgesia associated with ibuprofen arginine, etoricoxib and dexamethasone in bilateral extractions of mandibular third molars. Methods TFourty two volunteers (12 men and 30 women), took part in this randomized, blinded, parallel, clinical trial and were divided into 4 groups: group 1, who received 600mg of ibuprofen and 555mg of arginine, G2, treated with 90 mg etoricoxib, G3, receiving 8 mg dexamethasone and G4, treated with a placebo, administered orally 90 minutes prior to surgery. Pain intensity was assessed using a 101 point numerical scale (101P) and a 4-point verbal scale (VRS) after 2, 4, 6, 8, 12, 24, 36 and 48 hours. For the statistical analysis of the data,the Kruskal-Wallis test was employed (p≤0.05). Results The results showed that volunteers in G4 exhibitedmore pain than the other groups, at 4 and 12 hours. The G3 showed higher pain intensity than G2 at 2 hours via the VRS and at 6 hours with the 101P, and in comparison with G1 after 4 and 6 hours with the 101P. There was a statistical difference between G4 and G3 and between G4 and G2 when comparingthe consumption of pain relievers. Conclusion It was concluded that all the drugs evaluated promoted postoperative analgesia when compared to the placebo. The analgesic consumption is lower when employing etoricoxib or dexamethasone. This work filed inthe Clinical Trials Registerunder no.U1111-1129-1722.

Keywords : Anti-inflammatory agents.; Molar third.; Tooth extraction..